| Card no. | Player | Year | Set name | |
| 1 | Mark McGwire | 2000 | Topps Chrome | |
| 48 | Kent Bottenfield | 2000 | Topps Chrome | |
| 68 | Eli Marrero | 2000 | Topps Chrome | |
| 164 | Fernando Tatis | 2000 | Topps Chrome | |
| 190 | Eric Davis | 2000 | Topps Chrome | |
| 192 | Joe McEwing | 2000 | Topps Chrome | |
| 212 | Chance Caple | 2000 | Topps Chrome | |
| 218 | Jose Jimenez | 2000 | Topps Chrome | |
| 220 | Fernando Tatis | 2000 | Topps Chrome | |
| 232 | Mark McGwire | 2000 | Topps Chrome | |
| 236 | Mark McGwire | 2000 | Topps Chrome | |
| 245 | Ray Lankford | 2000 | Topps Chrome | |
| 352 | Edgar Renteria | 2000 | Topps Chrome | |
| 428 | Andy Benes | 2000 | Topps Chrome | |
| 456 | Mark McGwire | 2000 | Topps Chrome | |
| 462 | Mark McGwire | 2000 | Topps Chrome | |
| 463 | Mark McGwire | 2000 | Topps Chrome | |
| 469 | Mark McGwire | 2000 | Topps Chrome | |
| 1 | Mark McGwire | 2000 | Topps Chrome Refractors | |
| 48 | Kent Bottenfield | 2000 | Topps Chrome Refractors | |
| 68 | Eli Marrero | 2000 | Topps Chrome Refractors | |
| 164 | Fernando Tatis | 2000 | Topps Chrome Refractors | |
| 190 | Eric Davis | 2000 | Topps Chrome Refractors | |
| 192 | Joe McEwing | 2000 | Topps Chrome Refractors | |
| 212 | Chance Caple | 2000 | Topps Chrome Refractors | |
| 218 | Jose Jimenez | 2000 | Topps Chrome Refractors | |
| 220 | Fernando Tatis | 2000 | Topps Chrome Refractors | |
| 232 | Mark McGwire | 2000 | Topps Chrome Refractors | |
| 236a | Mark McGwire | 2000 | Topps Chrome Refractors | |
| 236b | Mark McGwire | 2000 | Topps Chrome Refractors | |
| 236c | Mark McGwire | 2000 | Topps Chrome Refractors | |
| 236d | Mark McGwire | 2000 | Topps Chrome Refractors | |
| 236e | Mark McGwire | 2000 | Topps Chrome Refractors | |
| 245 | Ray Lankford | 2000 | Topps Chrome Refractors | |
| 352 | Edgar Renteria | 2000 | Topps Chrome Refractors | |
| 428 | Andy Benes | 2000 | Topps Chrome Refractors | |
| 456 | Mark McGwire | 2000 | Topps Chrome Refractors | |
| 462 | Mark McGwire | 2000 | Topps Chrome Refractors | |
| 463 | Mark McGwire | 2000 | Topps Chrome Refractors | |
| 469 | Mark McGwire | 2000 | Topps Chrome Refractors | |
| 1 | Mark McGwire | 2000 | Topps Chrome All-Star Rookie Team | |
| 1 | Mark McGwire | 2000 | Topps Chrome All-Star Rookie Team Refractors | |
| 3 | Mark McGwire | 2000 | Topps Chrome All-Topps Team | |
| 3 | Mark McGwire | 2000 | Topps Chrome All-Topps Refractors | |
| 6 | Mark McGwire | 2000 | Topps Chrome Combos | |
| 6 | Mark McGwire | 2000 | Topps Chrome Combos Refractors | |
| 1 | Mark McGwire | 2000 | Topps Chrome Kings | |
| 1 | Mark McGwire | 2000 | Topps Chrome Kings Refractors | |
| 6 | Mark McGwire | 2000 | Topps Chrome Own the Game | |
| 7 | Mark McGwire | 2000 | Topps Chrome Own the Game | |
| 14 | Mark McGwire | 2000 | Topps Chrome Own the Game | |
| 6 | Mark McGwire | 2000 | Topps Chrome Own the Game Refractors | |
| 7 | Mark McGwire | 2000 | Topps Chrome Own the Game Refractors | |
| 14 | Mark McGwire | 2000 | Topps Chrome Own the Game Refractors | |
| 3 | Mark McGwire | 2000 | Topps Chrome Power Players | |
| 3 | Mark McGwire | 2000 | Topps Chrome Power Players Refractors | |
| 9 | Chance Caple | 2000 | Topps Chrome Traded and Rookies | |
| 35 | Ben Johnson | 2000 | Topps Chrome Traded and Rookies | |
| 91 | Jim Edmonds | 2000 | Topps Chrome Traded and Rookies | |
| 94 | Darryl Kile | 2000 | Topps Chrome Traded and Rookies | |
| 111 | Pat Hentgen | 2000 | Topps Chrome Traded and Rookies | |
| 116 | Fernando Vina | 2000 | Topps Chrome Traded and Rookies | |
| 129 | Will Clark | 2000 | Topps Chrome Traded and Rookies |